Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24607751 | 0.84 | CYP2D6 (0.42) | CYP2D6TSHRSMN1; SMN2USP2CYP1A2 | |
| SCHEMBL24673400 | 0.76 | CYP2D6 (0.38) | CYP2D6TSHRSMN1; SMN2USP2CYP1A2 | |
| SCHEMBL24508733 | 0.76 | CYP2D6 (0.38) | CYP2D6TSHRSMN1; SMN2USP2CYP1A2 | |
| SCHEMBL27281654 | 0.75 | CYP2D6 (0.47) | CYP2D6TSHRSMN1; SMN2USP2CYP1A2 | |
| SCHEMBL26445327 | 0.74 | CYP2D6 (0.37) | CYP2D6TSHRSMN1; SMN2USP2CYP1A2 | |
| SCHEMBL24841927 | 0.74 | CYP2D6 (0.37) | CYP2D6TSHRSMN1; SMN2USP2CYP1A2 | |
| SCHEMBL16999001 | 0.71 | CYP2D6 (0.45) | CYP2D6TSHRSMN1; SMN2USP2CYP1A2 | |
| SCHEMBL23770532 | 0.71 | CYP2D6 (0.45) | CYP2D6TSHRSMN1; SMN2USP2CYP1A2 | |
| SCHEMBL24498749 | 0.71 | PIK3CD (0.47) | CYP2D6SMN1; SMN2PIK3CD | |
| SCHEMBL23386075 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127278-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |