Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.49 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29498327 | 0.86 | MAP4K4 (0.54) | MAP4K4HDAC1GPR119SUV39H2GRM1 | |
| SCHEMBL31104870 | 0.86 | MAP4K4 (0.59) | MAP4K4HDAC1GPR119SUV39H2GRM1 | |
| SCHEMBL30426551 | 0.86 | MAP4K4 (0.59) | MAP4K4HDAC1GPR119SUV39H2GRM1 | |
| SCHEMBL31105042 | 0.86 | MAP4K4 (0.54) | MAP4K4HDAC1GPR119SUV39H2GRM1 | |
| SCHEMBL21484275 | 0.86 | MAP4K4 (0.59) | MAP4K4HDAC1GPR119SUV39H2GRM1 | |
| SCHEMBL29498324 | 0.86 | MAP4K4 (0.59) | MAP4K4HDAC1GPR119SUV39H2GRM1 | |
| SCHEMBL21483223 | 0.86 | MAP4K4 (0.59) | MAP4K4HDAC1GPR119SUV39H2GRM1 | |
| SCHEMBL21460229 | 0.86 | MAP4K4 (0.54) | MAP4K4HDAC1GPR119SUV39H2GRM1 | |
| SCHEMBL21460227 | 0.86 | MAP4K4 (0.54) | MAP4K4HDAC1GPR119SUV39H2GRM1 | |
| SCHEMBL30427123 | 0.86 | MAP4K4 (0.54) | MAP4K4HDAC1GPR119SUV39H2GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021123291-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-06-24 | — | — | WO | disclosed |