Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.67 |
| ▸ | BRD4 | O60885 | 2/20 | 0.58 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.58 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3648191 | 0.83 | CRBN (0.70) | CRBNBRD4DDB1IKZF3 | |
| SCHEMBL28814069 | 0.83 | CRBN (0.70) | CRBNBRD4DDB1IKZF3 | |
| SCHEMBL29923298 | 0.80 | CRBN (1.00) | CRBNBRD4DDB1IKZF3 | |
| SCHEMBL17169744 | 0.80 | CRBN (1.00) | CRBNBRD4DDB1IKZF3 | |
| SCHEMBL22511740 | 0.80 | CRBN (0.67) | CRBNBRD4DDB1IKZF3 | |
| SCHEMBL21751116 | 0.80 | CRBN (0.64) | CRBNBRD4DDB1IKZF3 | |
| Hydrochloric Acid SCHEMBL19359358 | 0.79 | CRBN (0.97) | CRBNBRD4DDB1IKZF3 | |
| SCHEMBL14560869 | 0.79 | CRBN (0.77) | CRBNBRD4DDB1IKZF3 | |
| SCHEMBL4781353 | 0.79 | CRBN (0.77) | CRBNBRD4DDB1IKZF3 | |
| SCHEMBL26646479 | 0.79 | CRBN (0.77) | CRBNBRD4DDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021126973-A1 | COMPOUNDS MODULATING PROTEIN RECRUITMENT AND/OR DEGRADATION | ORIONIS BIOSCIENCES, INC. (US) | 2021-06-24 | — | — | WO | disclosed |