SCHEMBL23565

SCHEMBL23565

C[C@@]12C(=CC(=O)C=C1OP(=O)(O)O)CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C)[C@H]1CC[C@]2(O)C(=O)CO.[NaH]

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 10/20 0.63
NR3C1 P04150 8/20 0.63
HSD17B10 Q99714 6/20 0.63
PGR P06401 5/20 0.63
CYP3A4 P08684 5/20 0.63
CYP2C19 P33261 3/20 0.63
SERPINA6 P08185 3/20 0.63
NR3C2 P08235 2/20 0.63
AR P10275 2/20 0.63
ABCB11 O95342 2/20 0.63
TNF P01375 1/20 0.63
IL6 P05231 1/20 0.63
GLUL P15104 1/20 0.63
ADAM17 P78536 1/20 0.63
GPBAR1 Q8TDU6 1/20 0.63
KMT2A Q03164 2/20 0.59
SHBG P04278 1/20 0.59
MAPT P10636 1/20 0.59
NFKB1 P19838 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28303115 1.00 HIF1A (0.63) HIF1ANR3C1HSD17B10PGRCYP3A4
SCHEMBL7513 0.99 HIF1A (0.64) HIF1ANR3C1HSD17B10PGRCYP3A4
SCHEMBL16094486 0.93 HIF1A (0.61) HIF1ANR3C1HSD17B10PGRCYP3A4
SCHEMBL28874596 0.93 HIF1A (0.61) HIF1ANR3C1HSD17B10PGRCYP3A4
SCHEMBL28596717 0.93 HIF1A (0.55) HIF1ANR3C1HSD17B10PGRCYP3A4
SCHEMBL23828321 0.92 HIF1A (0.61) HIF1ANR3C1HSD17B10PGRCYP3A4
SCHEMBL28388269 0.92 HIF1A (0.61) HIF1ANR3C1HSD17B10PGRCYP3A4
SCHEMBL1930094 0.92 HIF1A (0.63) HIF1ANR3C1HSD17B10PGRCYP3A4
Phosphoric Acid SCHEMBL27656886 0.90 HIF1A (0.61) HIF1ANR3C1HSD17B10PGRCYP3A4
SCHEMBL26126454 0.89 HIF1A (0.56) HIF1ANR3C1HSD17B10PGRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12027 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4701663-A1 PROLYL HYDROXYLASE DOMAIN-CONTAINING PROTEIN (PHD) INHIBITORS, COMBINATIONS AND USES THEREOF Insilico Medicine IP Limited (HK) 2026-03-04 EP claimed
EP-4590283-A1 MUCOADHESIVE DRUG DELIVERY SYSTEMS AND METHODS OF USE Madd Ophthalmics Ltd. (CA) 2025-07-30 EP claimed
US-12364682-B2 Use of tegaserod in preparation of anti-tumor drug QINGDAO HAIJI BIOMEDICINE CO., LTD. (CN) 2025-07-22 US claimed
EP-4580674-A2 ANTIGEN BINDING MOLECULES TARGETING PROGRAMMED CELL DEATH PROTEIN 1 (PD-1) Flagship Pioneering Innovations VI, LLC (US) 2025-07-09 EP claimed
CN-120154586-A Powder aerosol composition for inhalation, powder aerosol for inhalation, preparation method of powder aerosol for inhalation and powder aerosol for inhalation 上海臣邦医药科技股份有限公司 2025-06-17 CN claimed
US-20250186253-A1 DEVICES AND METHODS FOR ADJUSTING THE INSERTION DEPTH OF A NEEDLE FOR MEDICAMENT DELIVERY CLEARSIDE BIOMEDICAL, INC. (US) 2025-06-12 US claimed
CN-120022371-A Organic molecule self-assembly body used as material-free drug carrying system, and preparation method and application thereof 四川大学华西医院 2025-05-23 CN claimed
US-12285488-B2 Oral dosage form containing theobromine-free cocoa LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2025-04-29 US claimed
US-12274681-B2 Compositions and methods for reducing skin fat PURDUE RESEARCH FOUNDATION (US) 2025-04-15 US claimed
WO-2025076059-A1 ROCAGLATE DERIVATIVES AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2025-04-10 WO claimed
EP-0521074-A1 DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE. ALZA CORP (US) 1993-01-07 EP claimed
EP-0496520-A1 Novel bone acting agents MERCK & CO. INC. (US) 1992-07-29 EP claimed
WO-1991014426-A1 DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE ALZA CORPORATION (US) 1991-10-03 WO claimed
EP-0126684-B1 DRUG DELIVERY SYSTEM UTILIZING THERMOSETTING GELS MERCK & CO. INC. (US) 1991-08-28 EP claimed
US-4904474-A Delivery of drug to colon by oral disage form ALZA CORPORATION (US) 1990-02-27 US claimed
US-4579960-A ANTIMICROBIAL FOR EYES, NOSE SCHERING CORPORATION (US) 1986-04-01 US claimed
EP-0126684-A2 Drug delivery system utilizing thermosetting gels MERCK & CO. INC. (US) 1984-11-28 EP claimed
US-4474751-A SUSTAINED RELEASE USING AN ALKYLENEDIAMINE-MODIFIED ETHYLENE OXIDE-PROPYLENE OXIDE COPOLYMER MERCK & CO., INC. (US) 1984-10-02 US claimed
US-4448774-A PREDNISOLONE IN AQUEOUS SOLUTION FISONS CORPORATION (US) 1984-05-15 US claimed
US-4304765-A Ocular insert housing steroid in two different therapeutic forms ALZA CORPORATION (US) 1981-12-08 US claimed