SCHEMBL23565629

SCHEMBL23565629

C[C@@H]1Cc2ccc(CN3CCN(c4ncc5c(n4)CCNC5=O)CC3)cc2O1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OGA O60502 3/20 0.70
HTT P42858 5/20 0.45
LMNA P02545 5/20 0.45
ALDH1A1 P00352 5/20 0.45
TSHR P16473 4/20 0.45
USP2 O75604 4/20 0.45
HPGD P15428 3/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
KDM4E B2RXH2 2/20 0.45
SMN1; SMN2 Q16637 3/20 0.39
MAPT P10636 2/20 0.39
GAA P10253 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PARP1 P09874 2/20 0.38
PARP2 Q9UGN5 1/20 0.38
KCNH2 Q12809 2/20 0.37
AKT1 P31749 1/20 0.37
AKT2 P31751 1/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23314242 1.00 OGA (0.70) OGAHTTLMNAALDH1A1TSHR
SCHEMBL24283127 0.84 OGA (0.49) OGAHTTLMNAALDH1A1TSHR
SCHEMBL23314236 0.83 OGA (0.70) OGAHTTLMNAALDH1A1TSHR
SCHEMBL23282517 0.82 OGA (1.00) OGA
SCHEMBL23282494 0.82 OGA (1.00) OGA
SCHEMBL23282495 0.82 OGA (1.00) OGA
SCHEMBL23282532 0.82 OGA (1.00) OGA
SCHEMBL23282550 0.82 OGA (1.00) OGA
SCHEMBL23282496 0.82 OGA (1.00) OGA
SCHEMBL23282515 0.82 OGA (1.00) OGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3419972-B1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2023-07-26 EP disclosed
US-20210186958-A1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2021-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210186958-A1 GLYCOSIDASE INHIBITORS ENGASE, GAA, GLA OGA 73/4885HTT 315/4885LMNA 493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.