Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 11/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TOP1 | P11387 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 3/20 | 0.46 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23566023 | 0.92 | NQO2 (0.55) | NQO2PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL5142092 | 0.90 | NQO2 (0.57) | NQO2PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL23566337 | 0.89 | NQO2 (0.41) | NQO2PRMT1ALDH1A1TOP1HPGD | |
| Hydrochloric Acid SCHEMBL3363452 | 0.88 | TOP2A (0.58) | NQO2PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL23566270 | 0.86 | NQO2 (0.41) | NQO2PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL14089900 | 0.82 | NQO2 (0.49) | NQO2PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL14599571 | 0.81 | NQO2 (0.66) | NQO2PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL23566336 | 0.80 | APP (0.38) | NQO2PTPN1PTPN11 | |
| SCHEMBL14089897 | 0.78 | NQO2 (0.55) | NQO2PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL23566338 | 0.77 | NQO2 (0.41) | NQO2PRMT1ALDH1A1TOP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127452-A1 | COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION OF ANTIBIOTICS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-06-24 | — | — | WO | disclosed |