Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 10/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 10/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22518777 | 0.87 | TDP1 (0.54) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL17701139 | 0.87 | TDP1 (0.54) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL30337966 | 0.78 | FOLH1 (0.55) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL25963701 | 0.78 | FOLH1 (0.55) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL17701134 | 0.77 | FOLH1 (0.50) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL17701135 | 0.77 | FOLH1 (0.50) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL29465523 | 0.77 | FOLH1 (0.67) | TDP1NPSR1KMT2AMEN1MAPT | |
| SCHEMBL29679325 | 0.77 | FOLH1 (0.67) | TDP1NPSR1KMT2AMEN1MAPT | |
| SCHEMBL4330583 | 0.77 | FOLH1 (0.67) | TDP1NPSR1KMT2AMEN1MAPT | |
| SCHEMBL18161563 | 0.77 | FOLH1 (0.67) | TDP1NPSR1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021123013-A1 | SMART DRUG DELIVERY SYSTEM AND PHARMACEUTICAL KIT FOR DUAL NUCLEAR MEDICAL CYTOTOXIC THERANOSTICS | Johannes Gutenberg-Universität Mainz (DE) | 2021-06-24 | — | — | WO | disclosed |