Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 9/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.45 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 12/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 12/20 | 0.41 |
| ▸ | CDK9 | P50750 | 6/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.41 |
| ▸ | CDK7 | P50613 | 1/20 | 0.41 |
| ▸ | CCNH | P51946 | 1/20 | 0.41 |
| ▸ | CCNT2 | O60583 | 2/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23569988 | 0.93 | CDK2 (0.45) | CDK2CCNE1CCNE2CDK5CDK5R1 | |
| SCHEMBL23570179 | 0.93 | CDK2 (0.45) | CDK2CCNE1CCNE2CDK5CDK5R1 | |
| SCHEMBL22566856 | 0.87 | CDK2 (0.45) | CDK2CCNE1CCNE2CDK5CDK5R1 | |
| SCHEMBL21754255 | 0.87 | CDK5 (0.40) | CDK2CCNE1CCNE2CDK5CDK5R1 | |
| SCHEMBL23570213 | 0.86 | CDK2 (0.43) | CDK2CCNE1CCNE2CDK5CDK5R1 | |
| SCHEMBL23569885 | 0.86 | CDK2 (0.43) | CDK2CCNE1CCNE2CDK5CDK5R1 | |
| SCHEMBL19278523 | 0.84 | CDK2 (0.48) | CDK2CCNE1CCNE2CCNKCDK12 | |
| SCHEMBL19278339 | 0.84 | CDK2 (0.48) | CDK2CCNE1CCNE2CCNKCDK12 | |
| SCHEMBL23570181 | 0.84 | CDK2 (0.43) | CDK2CCNE1CCNE2CDK5CDK5R1 | |
| SCHEMBL19278526 | 0.84 | CDK2 (0.48) | CDK2CCNE1CCNE2CCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210187033-A1 | COMPOUNDS THAT EXPAND HEMATOPOIETIC STEM CELLS | NOVARTIS AG (CH) | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210187033-A1 | COMPOUNDS THAT EXPAND HEMATOPOIETIC STEM CELLS | CD47, HCLS1, CD74 | CDK2 3659/4885CCNE1 3047/4885CCNE2 3415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.