Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23573569 | 1.00 | POLB (0.59) | POLBL3MBTL1HSD17B10MAPK1EPHX2 | |
| SCHEMBL3196032 | 1.00 | POLB (0.59) | POLBL3MBTL1HSD17B10MAPK1EPHX2 | |
| SCHEMBL3196038 | 1.00 | POLB (0.59) | POLBL3MBTL1HSD17B10MAPK1EPHX2 | |
| SCHEMBL23573444 | 0.91 | POLB (0.50) | POLBL3MBTL1MAPK1EPHX2ALDH1A1 | |
| SCHEMBL23573428 | 0.91 | POLB (0.50) | POLBL3MBTL1MAPK1EPHX2ALDH1A1 | |
| SCHEMBL23573550 | 0.91 | POLB (0.50) | POLBL3MBTL1MAPK1EPHX2ALDH1A1 | |
| SCHEMBL23573549 | 0.91 | POLB (0.50) | POLBL3MBTL1MAPK1EPHX2ALDH1A1 | |
| SCHEMBL23573430 | 0.91 | POLB (0.50) | POLBL3MBTL1MAPK1EPHX2ALDH1A1 | |
| SCHEMBL103961 | 0.90 | — | — | |
| SCHEMBL22629764 | 0.86 | POLB (0.59) | POLBL3MBTL1HSD17B10MAPK1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210198239-A1 | COMPOUNDS AND METHODS FOR CD73 MODULATION AND INDICATIONS THEREFOR | PLEXXIKON INC. | 2021-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198239-A1 | COMPOUNDS AND METHODS FOR CD73 MODULATION AND INDICATIONS THEREFOR | ENTPD5, ADORA2A, ENTPD1 | POLB 1763/4885L3MBTL1 3541/4885HSD17B10 2865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.