Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adenosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 known ✓ | P30542 | 3/20 | 0.74 |
| ▸ | ADORA3 known ✓ | P0DMS8 | 1/20 | 0.74 |
| ▸ | ADORA2A known ✓ | P29274 | 1/20 | 0.74 |
| ▸ | ADORA2B known ✓ | P29275 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | DPP4 | P27487 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.74 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.74 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.74 |
| ▸ | GAPDH | P04406 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | STAT6 | P42226 | 1/20 | 0.74 |
| ▸ | PI4KA | P42356 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.74 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.74 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.74 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.74 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine SCHEMBL5474587 | 0.98 | ADORA1 (0.74) | ADORA1SMN1; SMN2DPP4MEN1SLC28A1 | |
| Adenosine SCHEMBL28652247 | 0.96 | P2RY2 (0.74) | ADORA1SMN1; SMN2DPP4MEN1SLC28A1 | |
| Adenosine SCHEMBL6051810 | 0.96 | ADORA1 (0.77) | ADORA1SMN1; SMN2DPP4MEN1SLC28A1 | |
| Adenosine SCHEMBL4762692 | 0.95 | SMN1; SMN2 (0.75) | ADORA1SMN1; SMN2DPP4MEN1SLC28A1 | |
| Adenosine SCHEMBL5495320 | 0.95 | ADORA1 (0.75) | ADORA1SMN1; SMN2DPP4MEN1SLC28A1 | |
| Adenosine SCHEMBL5903597 | 0.95 | ADORA1 (0.75) | ADORA1SMN1; SMN2DPP4MEN1SLC28A1 | |
| Adenosine SCHEMBL31308570 | 0.94 | ADORA1 (0.74) | ADORA1SMN1; SMN2DPP4MEN1SLC28A1 | |
| Adenosine SCHEMBL2248155 | 0.94 | ADORA1 (0.74) | ADORA1SMN1; SMN2DPP4MEN1SLC28A1 | |
| Adenosine SCHEMBL11579590 | 0.94 | ADORA1 (0.74) | ADORA1SMN1; SMN2DPP4MEN1SLC28A1 | |
| Adenosine SCHEMBL30165599 | 0.94 | P2RY2 (0.75) | ADORA1SMN1; SMN2DPP4MEN1SLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119291207-A | Composition, device and detection method for determining platelet number | 北京睿瑧生物技术有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-116223821-A | Platelet aggregation function detection reagent and application thereof | 上海太阳生物技术有限公司 | 2023-06-06 | — | — | CN | claimed |
| WO-2025090025-A1 | SILICON NANOCOMPOSITE ANODE | VOLT14 SOLUTIONS PTE. LTD. (SG) | 2025-05-01 | — | — | WO | disclosed |
| CN-119291207-A | Composition, device and detection method for determining platelet number | 北京睿瑧生物技术有限公司 | 2025-01-10 | — | — | CN | disclosed |
| WO-2024216536-A1 | METHOD FOR PREPARING RIBONUCLEOSIDE OR DERIVATIVE THEREOF, AND BIOLOGICAL ENZYME PREPARATION AND APPLICATION THEREOF | 百瑞全球有限公司 | 2024-10-24 | — | — | WO | disclosed |
| CN-116223821-A | Platelet aggregation function detection reagent and application thereof | 上海太阳生物技术有限公司 | 2023-06-06 | — | — | CN | disclosed |
| EP-1637152-B1 | A NOTOGINSENG SAPONIN INTRAVENOUS INJECTION AND THE METHOD FOR PREPARING THIS INJECTION | LI MIN PHARMACEUTICAL FACTORY OF LIVZON PHARMCEUTICAL GROUP (CN) | 2011-08-10 | — | — | EP | disclosed |
| EP-1342462-B1 | O/W EMULSION COMPOSITION AND METHOD OF PREPARING THE SAME | OTSUKA PHARMA CO LTD (JP) | 2007-04-11 | — | — | EP | disclosed |
| US-20060141070-A1 | Notoginseng saponin intravenous injection and the method for preparing this injection | LI MIN PHARMACEUTICAL FACTORY OF LIVZON PHARMACEUTICAL GROUP (CN) | 2006-06-29 | — | — | US | disclosed |
| EP-1637152-A1 | A NOTOGINSENG SAPONIN INTRAVENOUS INJECTION AND THE METHOD FOR PREPARING THIS INJECTION | Li Min Pharmaceutical Factory of Livzon Pharmaceutical (CN) | 2006-03-22 | — | — | EP | disclosed |
| US-6946436-B2 | O/W emulsion composition and method of preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-09-20 | — | — | US | disclosed |
| US-20040029761-A1 | O/W emulsion composition and method of preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-12 | — | — | US | disclosed |
| EP-1342462-A1 | O/W EMULSION COMPOSITION AND METHOD OF PREPARING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-4091222-A | ANTIINFLAMMATORY, ANTIPYRETIC, ANALGESIC, ANTITUSSIVE, CNS EFFECTS, ANAESTHETICS, ANTIARRHYTHMIC, HYPOTENSIVE, ANTICOAGULANTS | MANGHISI ELSO | 1978-05-23 | — | — | US | disclosed |
| US-4061637-A | CNS, CARDIOVASCULAR, ANTIINFLAMMATORY, ADRENOLYTIC, ANTIULCER | ISTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) | 1977-12-06 | — | — | US | disclosed |
| US-3988475-A | ANAESTHETICS, ANTIARRHYTHMIA, HYPOTENSIVES, ADRENERGIC | ISTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) | 1976-10-26 | — | — | US | disclosed |
| US-3970672-A | 2,2 Disubstituted-benzodioxoles | ISTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) | 1976-07-20 | — | — | US | disclosed |