Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 18/20 | 1.00 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19701240 | 1.00 | SMYD3 (1.00) | SMYD3PARP1ADORA1 | |
| SCHEMBL244445 | 0.81 | SMYD3 (0.67) | SMYD3PARP1ADORA1 | |
| SCHEMBL25692414 | 0.81 | SMYD3 (0.67) | SMYD3PARP1 | |
| SCHEMBL244667 | 0.80 | SMYD3 (0.66) | SMYD3PARP1ADORA1 | |
| SCHEMBL12257089 | 0.80 | SMYD3 (0.66) | SMYD3PARP1ADORA1 | |
| SCHEMBL21489836 | 0.76 | SMYD3 (1.00) | SMYD3 | |
| SCHEMBL19701229 | 0.76 | SMYD3 (1.00) | SMYD3 | |
| SCHEMBL12233638 | 0.76 | SMYD3 (0.61) | SMYD3PARP1ADORA1 | |
| SCHEMBL21489911 | 0.75 | SMYD3 (0.71) | SMYD3 | |
| SCHEMBL19701228 | 0.75 | SMYD3 (0.71) | SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210198252-A1 | SMYD INHIBITORS | EPIZYME INC (US) | 2021-07-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198252-A1 | SMYD INHIBITORS | SMYD3, SMYD2, SMURF2 | SMYD3 1/4885PARP1 4583/4885ADORA1 4735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.