Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 20/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | EZH1 | Q92800 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29741587 | 1.00 | EZH2 (0.47) | EZH2KCNH2EZH1 | |
| SCHEMBL23581392 | 1.00 | EZH2 (0.47) | EZH2KCNH2EZH1 | |
| SCHEMBL23672219 | 0.90 | EZH2 (0.54) | EZH2KCNH2EZH1 | |
| SCHEMBL23672216 | 0.90 | EZH2 (0.54) | EZH2KCNH2EZH1 | |
| SCHEMBL29966180 | 0.89 | EZH2 (0.58) | EZH2 | |
| SCHEMBL16376976 | 0.89 | EZH2 (0.47) | EZH2KCNH2EZH1 | |
| SCHEMBL23606586 | 0.89 | EZH2 (0.58) | EZH2 | |
| SCHEMBL23606650 | 0.87 | EZH2 (0.46) | EZH2KCNH2EZH1 | |
| SCHEMBL23682342 | 0.86 | EZH2 (0.55) | EZH2 | |
| SCHEMBL23581333 | 0.86 | EZH2 (0.49) | EZH2KCNH2EZH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787143-A | ZESTE enhancer homolog 2 inhibitors and uses thereof | 四川海思科制药有限公司 | 2022-07-22 | — | — | CN | disclosed |
| WO-2021129629-A1 | ZESTE ENHANCER HOMOLOGUE 2 INHIBITOR AND USE THEREOF | 四川海思科制药有限公司 | 2021-07-01 | — | — | WO | disclosed |