⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28018238 | 0.83 | TDP1 (0.39) | — | |
| SCHEMBL7922034 | 0.77 | — | — | |
| SCHEMBL7141795 | 0.77 | — | — | |
| SCHEMBL7907833 | 0.77 | — | — | |
| SCHEMBL27882772 | 0.74 | — | — | |
| SCHEMBL21738103 | 0.71 | — | — | |
| SCHEMBL13574546 | 0.69 | — | — | |
| SCHEMBL27847459 | 0.68 | — | — | |
| SCHEMBL27326260 | 0.65 | — | — | |
| SCHEMBL27326265 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426664-B1 | SUBSTITUTED NUCLEOSIDE ANALOGUES FOR USE AS PRMT5 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2021-06-30 | — | — | EP | disclosed |