Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15660607 | 0.86 | PDE4B (0.61) | PDE4BPDE4D | |
| SCHEMBL15657624 | 0.86 | PDE4B (0.68) | PDE4BPDE4D | |
| SCHEMBL15658466 | 0.85 | PDE4B (0.81) | PDE4BPDE4D | |
| SCHEMBL23586199 | 0.84 | PDE4B (0.61) | PDE4BPDE4D | |
| SCHEMBL15658630 | 0.84 | PDE4B (0.58) | PDE4BPDE4D | |
| SCHEMBL23586247 | 0.82 | PDE4B (0.59) | PDE4BPDE4D | |
| SCHEMBL15659184 | 0.81 | PDE4B (0.54) | PDE4BPDE4D | |
| SCHEMBL23586242 | 0.80 | PDE4B (0.65) | PDE4BPDE4D | |
| SCHEMBL15660334 | 0.80 | PDE4B (0.63) | PDE4BPDE4D | |
| SCHEMBL15661255 | 0.80 | PDE4B (0.60) | PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842420-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners LLC (US) | 2021-06-30 | — | — | EP | disclosed |