Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23526899 | 1.00 | USP30 (0.44) | USP30TACR1EPHX2GPR119STS | |
| SCHEMBL23526875 | 0.92 | TACR1 (0.43) | USP30TACR1EPHX2GPR119STS | |
| SCHEMBL30900988 | 0.92 | TACR1 (0.43) | USP30TACR1EPHX2GPR119STS | |
| SCHEMBL23527274 | 0.90 | USP30 (0.46) | USP30TACR1EPHX2GPR119STS | |
| SCHEMBL23527167 | 0.88 | USP30 (0.46) | USP30TACR1EPHX2GPR119STS | |
| SCHEMBL23564392 | 0.88 | USP30 (0.46) | USP30TACR1EPHX2GPR119STS | |
| SCHEMBL23527331 | 0.88 | EPHX2 (0.46) | EPHX2MGLLABHD6UBE2MDCUN1D1 | |
| SCHEMBL30900019 | 0.87 | TACR1 (0.44) | USP30TACR1EPHX2GPR119STS | |
| SCHEMBL23526921 | 0.87 | USP30 (0.46) | USP30TACR1EPHX2GPR119STS | |
| SCHEMBL23527180 | 0.87 | USP30 (0.46) | USP30TACR1EPHX2GPR119STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133750-A1 | SUBSTITUTED BICYCLIC PIPERIDINE DERIVATIVES USEFUL AS T CELL ACTIVATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-07-01 | — | — | WO | disclosed |