Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.53 |
| ▸ | HASPIN | Q8TF76 | 4/20 | 0.53 |
| ▸ | CDC7 | O00311 | 8/20 | 0.52 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.51 |
| ▸ | CDK9 | P50750 | 2/20 | 0.51 |
| ▸ | PIM1 | P11309 | 2/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23600199 | 0.79 | CHEK1 (0.56) | KMT2ACHEK1HASPINCDC7CCNT1 | |
| SCHEMBL23578828 | 0.76 | CHEK1 (0.56) | KMT2ACHEK1HASPINCCNT1CDK9 | |
| SCHEMBL23578825 | 0.76 | CHEK1 (0.56) | KMT2ACHEK1HASPINCCNT1CDK9 | |
| SCHEMBL1714207 | 0.76 | KMT2A (0.57) | KMT2ACHEK1HASPINCDC7CCNT1 | |
| SCHEMBL1714205 | 0.76 | KMT2A (0.57) | KMT2ACHEK1HASPINCDC7CCNT1 | |
| SCHEMBL23582994 | 0.74 | PIM1 (0.54) | KMT2ACHEK1HASPINCCNT1CDK9 | |
| SCHEMBL4959425 | 0.74 | PIM1 (0.54) | KMT2ACHEK1HASPINCCNT1CDK9 | |
| SCHEMBL4959430 | 0.74 | PIM1 (0.54) | KMT2ACHEK1HASPINCCNT1CDK9 | |
| SCHEMBL12506274 | 0.74 | CHEK1 (0.54) | KMT2ACHEK1HASPINCDC7CCNT1 | |
| SCHEMBL23600236 | 0.74 | HASPIN (0.54) | KMT2ACHEK1HASPINCDC7CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133037-A1 | PYRROLIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING BETA-AMYLOID OR TAU PROTEIN-ASSOCIATED DISEASES CONTAINING SAME | 연세대학교 산학협력단 | 2021-07-01 | — | — | WO | disclosed |