Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20231015 | 0.81 | TRIM24 (0.44) | AKR1C3KMT2AUSP2ALDH1A1GAA | |
| SCHEMBL21877408 | 0.80 | AKR1C3 (0.38) | AKR1C3FAAHMGLLALDH1A1TRIM24 | |
| SCHEMBL31753433 | 0.77 | HRH3 (0.49) | ALDH1A1MEN1KDM4EHRH3 | |
| SCHEMBL25170783 | 0.74 | MAPT (0.54) | AKR1C3KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL31465552 | 0.72 | KDM1A (0.40) | AKR1C3FAAHMGLLKMT2AUSP2 | |
| SCHEMBL30802795 | 0.71 | HRH3 (0.42) | HRH3 | |
| SCHEMBL22804834 | 0.71 | NOTUM (0.51) | AKR1C3KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL22796086 | 0.69 | KDM1A (0.38) | AKR1C3FAAHMGLLKMT2AUSP2 | |
| SCHEMBL16503327 | 0.69 | HRH3 (0.38) | AKR1C3FAAHMGLLKMT2AUSP2 | |
| SCHEMBL24624127 | 0.69 | KDM1A (0.38) | AKR1C3FAAHMGLLKMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4541795-A1 | AROMATIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF IN PREPARATION OF ESTROGEN RECEPTOR DEGRADER | Hinova Pharmaceuticals Inc. (CN) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023241598-A1 | AROMATIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF IN PREPARATION OF ESTROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-12-21 | — | — | WO | disclosed |
| CN-117229286-A | Aromatic compound, preparation method thereof and application thereof in preparation of estrogen receptor degradation agent | 海创药业股份有限公司 | 2023-12-15 | — | — | CN | disclosed |
| WO-2021129653-A1 | PROTEIN DEGRADATION AGENT COMPOUND PREPARATION METHOD AND APPLICATION | 上海济煜医药科技有限公司 | 2021-07-01 | — | — | WO | disclosed |