SCHEMBL2360411

SCHEMBL2360411

C1=NC=C2NCNN2C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL195402 0.65
SCHEMBL30995335 0.60
Hydrochloric Acid SCHEMBL28204779 0.31
Hydrochloric Acid SCHEMBL444225 0.29
Hydrochloric Acid SCHEMBL2097144 0.29
Hydrochloric Acid SCHEMBL11049151 0.29
Hydrochloric Acid SCHEMBL1449238 0.29
Hydrochloric Acid SCHEMBL6244319 0.29
Hydrochloric Acid SCHEMBL72335 0.29
Hydrochloric Acid SCHEMBL704 0.29

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3672958-B1 ANNULATED GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2023-08-02 EP disclosed
US-11458140-B2 Annulated glycosidase inhibitors ASCENEURON SA (CH) 2022-10-04 US disclosed
US-20200289516-A1 ANNULATED GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2020-09-17 US disclosed
EP-3672958-A1 ANNULATED GLYCOSIDASE INHIBITORS Asceneuron SA (CH) 2020-07-01 EP disclosed
WO-2019037861-A1 ANNULATED GLYCOSIDASE INHIBITORS Asceneuron S.A. (CH) 2019-02-28 WO disclosed
EP-2536706-A1 ARYLMETHOXY ISOINDOLINE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME Celgene Corporation (US) 2012-12-26 EP disclosed
WO-2011100380-A1 ARYLMETHOXY ISOINDOLINE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME CELGENE CORPORATION (US) 2011-08-18 WO disclosed
EP-2124913-A1 1-AMINOMETHYL- L- PHENYL- CYCLOHEXANE DERIVATIVES AS DDP-IV INHIBITORS Novartis AG (CH) 2009-12-02 EP disclosed
US-7482336-B2 Aminocyclohexanes as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes MERCK & CO., INC. (US) 2009-01-27 US disclosed
WO-2008077597-A1 1-AMINOMETHYL- L- PHENYL- CYCLOHEXANE DERIVATIVES AS DDP-IV INHIBITORS NOVARTIS AG (CH) 2008-07-03 WO disclosed