SCHEMBL2360490

SCHEMBL2360490

Cc1cccc(CCCl)c1

nearest known ligand 0.63

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.63
HRH3 Q9Y5N1 3/20 0.52
IDO1 P14902 2/20 0.50
ACHE P22303 1/20 0.48
GPR84 Q9NQS5 1/20 0.47
DAO P14920 3/20 0.46
CNR1 P21554 1/20 0.43
MAOB P27338 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL1789063 0.89 TAAR1 (0.52) TAAR1HRH3IDO1GPR84DAO
SCHEMBL11713410 0.87 TAAR1 (0.59) TAAR1HRH3IDO1ACHEGPR84
SCHEMBL29596752 0.85 TAAR1 (0.74) TAAR1HRH3IDO1ACHEGPR84
SCHEMBL8096473 0.85 TAAR1 (0.74) TAAR1HRH3IDO1ACHEGPR84
SCHEMBL5248849 0.85 TAAR1 (0.57) TAAR1HRH3IDO1ACHEDAO
SCHEMBL8897767 0.83 MEN1 (0.48) TAAR1MAOB
SCHEMBL30084583 0.81
SCHEMBL52147 0.81
SCHEMBL8092500 0.81 TAAR1 (0.68) TAAR1HRH3IDO1ACHEGPR84
SCHEMBL8099771 0.81 TAAR1 (0.68) TAAR1HRH3IDO1ACHEGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3962357-A FROM SUBSTITUTED ETHYLTOLUENE, CONTINUOUS, SINGLE STEP ROHM AND HAAS COMPANY (US) 1976-06-08 US claimed
CN-119264430-A Synthetic preparation method of polybenzimidazole resin 广州瑞博新材料技术研究有限公司 2025-01-07 CN disclosed
EP-4257593-A1 CHIRAL MULTIDENTATE LIGAND AND USE THEREOF IN ASYMMETRIC HYDROGENATION SHENZHEN CATALYS TECHNOLOGY CO., LTD. (CN) 2023-10-11 EP disclosed
CN-110669743-A P450 monooxygenase mutant from deinococcus radiodurans and application thereof 遵义医科大学 2020-01-10 CN disclosed
CN-103787993-B Quinoxaline-2 (1H)-one compounds and its preparation method and application BEIJING UNIVERSITY OF TECHNOLOGY (CN) 2016-04-27 CN disclosed
CN-103787993-A Quinoxaline-2(1H)-ketone compound, preparation method and application thereof UNIV BEIJING TECHNOLOGY 2014-05-14 CN disclosed
EP-2356114-A1 AMINOALKYL-SUBSTITUTED COMPOUNDS AS HIF INHIBITORS Bayer Schering Pharma Aktiengesellschaft (DE) 2011-08-17 EP disclosed
WO-2010054762-A1 AMINOALKYL-SUBSTITUTED COMPOUNDS AS HIF INHIBITORS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2010-05-20 WO disclosed
WO-1998010286-A1 METHODS FOR PROCESSING CHEMICAL COMPOUNDS HAVING REACTIVE FUNCTIONAL GROUPS ISIS PHARMACEUTICALS, INC. (US) 1998-03-12 WO disclosed
US-3962357-A FROM SUBSTITUTED ETHYLTOLUENE, CONTINUOUS, SINGLE STEP ROHM AND HAAS COMPANY (US) 1976-06-08 US disclosed