Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11419153 | 1.00 | — | — | |
| Bromide SCHEMBL29035800 | 0.87 | — | — | |
| Bromide SCHEMBL10457047 | 0.82 | — | — | |
| Bromide SCHEMBL1032276 | 0.82 | — | — | |
| Bromide SCHEMBL1030524 | 0.82 | — | — | |
| Bromide SCHEMBL23853041 | 0.82 | — | — | |
| Bromide SCHEMBL11503584 | 0.82 | — | — | |
| Bromide SCHEMBL1029370 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL8905191 | 0.82 | — | — | |
| Bromide SCHEMBL10427946 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317662-A | Trihalide perovskite layer, perovskite single junction solar cell, perovskite silicon laminated solar cell and preparation method thereof | 电子科技大学 | 2024-07-09 | — | — | CN | disclosed |
| WO-2020203496-A1 | METHOD FOR CONSTRUCTING CHIMERIC PLASMID LIBRARY | 国立大学法人神戸大学 | 2020-10-08 | — | — | WO | disclosed |
| CN-107681054-B | Preparation method of perovskite crystal nanowire | 上海理工大学 | 2020-01-21 | — | — | CN | disclosed |
| CN-110041915-A | The preparation method of perovskite quantum dot and metal organic frame composite luminescent material | 深圳大学 | 2019-07-23 | — | — | CN | disclosed |
| CN-107681054-A | A kind of preparation method of perovskite crystal nano wire | 上海理工大学 | 2018-02-09 | — | — | CN | disclosed |
| US-20140212413-A1 | Methods of Treating TNF-alpha-Mediated Diseases Using Chimeric TNF-alpha Antibodies | NEW YORK UNIVERSITY (US) | 2014-07-31 | — | — | US | disclosed |
| US-20130183298-A1 | Methods of Treating Hepatitis With Anti-TNF alpha Antibodies | NEW YORK UNIVERSITY (US) | 2013-07-18 | — | — | US | disclosed |
| US-20130171136-A1 | Methods of Treating Giant Cell Arteritis With Anti-TNF Alpha Antibodies | NEW YORK UNIVERSITY (US) | 2013-07-04 | — | — | US | disclosed |
| US-20110195063-A1 | Methods of Treating Ankylosing Spondylitis Using Anti-TNF Antibodies and Peptides of Human Tumor Necrosis Factor | CENTOCOR, INC. (US) | 2011-08-11 | — | — | US | disclosed |
| US-7744885-B2 | Methods of treating vascular inflammatory pathology using anti-TNF antibodies and fragments thereof | CENTOCOR, INC. (US) | 2010-06-29 | — | — | US | disclosed |
| EP-0493433-B1 | METHOD FOR IMPROVING HUMAN MONOCLONAL ANTIBODY PRODUCTION AND CELLS USED THEREIN | CENTOCOR INC (US) | 1996-01-10 | — | — | EP | disclosed |
| WO-1995012412-A1 | PLATELET-SPECIFIC CHIMERIC IMMUNOGLOBULIN AND METHODS OF USE THEREFOR | CENTOCOR, INC. (US) | 1995-05-11 | — | — | WO | disclosed |
| WO-1994018834-A1 | POLYELECTROLYTE DNA CONJUGATION AND GENETIC TRANSFORMATION OF AN ANIMAL | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1994-09-01 | — | — | WO | disclosed |
| EP-0610201-A1 | MONOCLONAL AND CHIMERIC ANTIBODIES SPECIFIC FOR HUMAN TUMOR NECROSIS FACTOR | NEW YORK UNIVERSITY (US) | 1994-08-17 | — | — | EP | disclosed |
| WO-1992016553-A1 | MONOCLONAL AND CHIMERIC ANTIBODIES SPECIFIC FOR HUMAN TUMOR NECROSIS FACTOR | NEW YORK UNIVERSITY (US) | 1992-10-01 | — | — | WO | disclosed |
| EP-0493433-A1 | METHOD FOR IMPROVING HUMAN MONOCLONAL ANTIBODY PRODUCTION. | CENTOCOR INC (US) | 1992-07-08 | — | — | EP | disclosed |
| WO-1991004336-A1 | METHOD FOR IMPROVING HUMAN MONOCLONAL ANTIBODY PRODUCTION | CENTOCOR, INC. (US) | 1991-04-04 | — | — | WO | disclosed |
| EP-0418316-A1 | PLATELET-SPECIFIC CHIMERIC IMMUNOGLOBULIN | CENTOCOR, INC. (US) | 1991-03-27 | — | — | EP | disclosed |
| WO-1989011538-A1 | PLATELET-SPECIFIC CHIMERIC IMMUNOGLOBULIN | CENTOCOR, INC. (US) | 1989-11-30 | — | — | WO | disclosed |
| US-4703012-A | High copy-number plasmid vectors, production and use thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1987-10-27 | — | — | US | disclosed |