SCHEMBL23606263

SCHEMBL23606263

c1ccc(-c2nc(-c3cccc(-c4cccc(-c5cccc6c5-c5ccccc5C65C6CC7CC(C6)CC5C7)c4)c3)nc(-c3cccc4ccccc34)n2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
NFKB1 P19838 1/20 0.34
MAPK1 P28482 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
ATM Q13315 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HTT P42858 1/20 0.33
CHRNA1 P02708 1/20 0.31
CHRNG P07510 1/20 0.31
CHRNB1 P11230 1/20 0.31
CHRNB2 P17787 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23609821 0.95 KDM4E (0.33) TSHRKDM4EALDH1A1TP53MAPT
SCHEMBL23605905 0.93 HTT (0.37) TSHRHTTADORA3ALOX15ADORA2A
SCHEMBL25038051 0.89 HTT (0.33) HTT
SCHEMBL24617964 0.87 HTT (0.35) TSHRALDH1A1MAPTHPGDHTT
SCHEMBL24617988 0.87 HTT (0.38) TSHRALDH1A1MAPTHPGDMAPK1
SCHEMBL24618077 0.87 HTT (0.38) TSHRALDH1A1MAPTHPGDMAPK1
SCHEMBL24618038 0.87 HTT (0.39) TSHRKDM4EALDH1A1MAPTHPGD
SCHEMBL24618035 0.86 HTT (0.34) TSHRKDM4EALDH1A1MAPTHPGD
SCHEMBL24618041 0.86 HTT (0.34) HTT
SCHEMBL25038248 0.86 HTT (0.34) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021128764-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2021-07-01 WO disclosed