SCHEMBL2360686

SCHEMBL2360686

COC(C)c1nc2c(c(C(C)C)c1C(O)c1ccc(C(F)(F)F)cc1)C(O[Si](C)(C)C(C)(C)C)CC(C)(C)C2

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL970464 1.00 CETP (0.51) CETP
SCHEMBL12921454 0.89 CETP (0.63) CETP
SCHEMBL12921455 0.88 CETP (0.64) CETP
SCHEMBL972171 0.87 CETP (0.55) CETP
SCHEMBL971353 0.87 CETP (0.48) CETP
SCHEMBL972169 0.87 CETP (0.55) CETP
SCHEMBL13691982 0.86 CETP (0.65) CETP
SCHEMBL662551 0.85 CETP (0.58) CETP
SCHEMBL662552 0.85 CETP (0.58) CETP
SCHEMBL16258318 0.85 CETP (0.58) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2268644-B1 TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION BOEHRINGER INGELHEIM INT (DE) 2011-08-17 EP disclosed