Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23609023 | 0.93 | CSNK2A2 (0.46) | SMN1; SMN2HTTKDM4EMAPTLMNA | |
| SCHEMBL23609161 | 0.91 | SMN1; SMN2 (0.44) | SMN1; SMN2HTTKDM4EMAPTLMNA | |
| SCHEMBL23608999 | 0.86 | CYP19A1 (0.43) | SMN1; SMN2HTTKDM4EMAPTLMNA | |
| SCHEMBL30406759 | 0.85 | HTT (0.40) | SMN1; SMN2HTTKDM4EMAPTLMNA | |
| SCHEMBL23609007 | 0.85 | HTT (0.40) | SMN1; SMN2HTTKDM4EMAPTLMNA | |
| SCHEMBL23609006 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2HTTKDM4EMAPTLMNA | |
| SCHEMBL23609019 | 0.84 | CSNK2A2 (0.46) | SMN1; SMN2HTTKDM4EMAPTLMNA | |
| SCHEMBL23609000 | 0.84 | CSNK2A2 (0.42) | SMN1; SMN2HTTKDM4EMAPTLMNA | |
| SCHEMBL23609230 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2HTTKDM4EMAPTLMNA | |
| SCHEMBL23609075 | 0.82 | CYP26A1 (0.40) | SMN1; SMN2HTTKDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |