Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 19/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 14/20 | 0.47 |
| ▸ | MTOR | P42345 | 14/20 | 0.47 |
| ▸ | ATR | Q13535 | 3/20 | 0.45 |
| ▸ | PRKDC | P78527 | 4/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24771785 | 0.86 | ATM (0.51) | ATMPIK3CAMTORATRPRKDC | |
| SCHEMBL21851154 | 0.83 | ATM (0.59) | ATMPIK3CAMTORATRPRKDC | |
| SCHEMBL24772413 | 0.81 | ATM (0.57) | ATMPIK3CAMTORATRPRKDC | |
| SCHEMBL24772323 | 0.76 | ATM (0.51) | ATMPIK3CAMTORATRPRKDC | |
| SCHEMBL21513239 | 0.74 | ATM (0.61) | ATMPIK3CAMTORATRPRKDC | |
| SCHEMBL29968606 | 0.74 | ATM (0.61) | ATMPIK3CAMTORATRPRKDC | |
| SCHEMBL21851070 | 0.73 | ATM (0.47) | ATMPIK3CAMTORATRPRKDC | |
| SCHEMBL21851064 | 0.73 | ATM (0.56) | ATMPIK3CAMTORATRPRKDC | |
| SCHEMBL21851122 | 0.73 | ATM (0.56) | ATMPIK3CAMTORATRPRKDC | |
| SCHEMBL21851057 | 0.73 | ATM (0.60) | ATMPIK3CAMTORATRPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3845532-A1 | QUINOLINO-PYRROLIDIN-2-ONE DERIVATIVE AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2021-07-07 | — | — | EP | disclosed |