SCHEMBL23616397

SCHEMBL23616397

FC(F)(Cc1ccc(Br)cc1)c1ccc(Br)cc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA5A P35218 1/20 0.41
CA9 Q16790 1/20 0.41
TAAR1 Q96RJ0 4/20 0.38
HTR2A P28223 1/20 0.38
IDO1 P14902 3/20 0.37
CYP2A6 P11509 1/20 0.36
ALDH1A1 P00352 1/20 0.35
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35
PTPRC P08575 1/20 0.34
PTPN2 P17706 1/20 0.34
PTPN1 P18031 1/20 0.34
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
PYCR1 P32322 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18550460 0.90 SLC6A2 (0.41) CA1CA2CA5ACA9HTR2A
SCHEMBL148198 0.78 TAAR1 (0.42) CA1CA2CA5ACA9TAAR1
SCHEMBL18550059 0.77 MEN1 (0.44) TAAR1IDO1ALDH1A1
SCHEMBL19510596 0.76 CA1 (0.43) CA1CA2CA5ACA9TAAR1
SCHEMBL15974610 0.76 CA1 (0.43) CA1CA2CA5ACA9TAAR1
SCHEMBL11922 0.74 CA1 (0.42) CA1CA2CA5ACA9CYP2A6
SCHEMBL11579 0.74 CA1 (0.42) CA1CA2CA5ACA9CYP2A6
SCHEMBL9063945 0.74 CA1 (0.42) CA1CA2CA5ACA9TAAR1
SCHEMBL17723819 0.74 CA1 (0.47) CA1CA2CA5ACA9TAAR1
SCHEMBL16685648 0.74 ESR1 (0.43) TAAR1HTR2AIDO1CYP2A6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3845579-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2021-07-07 EP disclosed