Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15988677 | 0.83 | GSK3B (0.48) | GSK3BMAPTKDM4EDAOALDH1A1 | |
| SCHEMBL12294979 | 0.81 | GSK3B (0.67) | GSK3BMAPTKDM4EDAOALDH1A1 | |
| SCHEMBL23617817 | 0.81 | GSK3B (0.46) | GSK3BMAPTDAOALDH1A1MEN1 | |
| SCHEMBL20488132 | 0.80 | GSK3B (0.40) | GSK3BMAPTKDM4EDAOALDH1A1 | |
| SCHEMBL18355585 | 0.80 | GSK3B (0.68) | GSK3BMAPTKDM4EDAOALDH1A1 | |
| SCHEMBL45690 | 0.79 | MAPT (0.42) | GSK3BMAPTKDM4EDAOALDH1A1 | |
| SCHEMBL15979710 | 0.77 | MEN1 (0.52) | GSK3BMAPTKDM4EDAOALDH1A1 | |
| SCHEMBL1472954 | 0.75 | DAO (0.63) | GSK3BMAPTKDM4EDAOALDH1A1 | |
| SCHEMBL17529446 | 0.75 | GSK3B (0.41) | GSK3BMAPTKDM4EDAOALDH1A1 | |
| SCHEMBL22870146 | 0.74 | KDM4E (0.54) | MAPTKDM4EDAOALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3589630-B1 | CYCLIC SULFAMIDE COMPOUNDS AND METHODS OF USING SAME | ASSEMBLY BIOSCIENCES INC (US) | 2021-07-07 | — | — | EP | disclosed |