⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3897224 | 0.62 | — | — | |
| SCHEMBL13069964 | 0.60 | — | — | |
| SCHEMBL10455845 | 0.59 | — | — | |
| SCHEMBL20729992 | 0.57 | — | — | |
| SCHEMBL21780779 | 0.56 | — | — | |
| SCHEMBL5345820 | 0.55 | — | — | |
| SCHEMBL17922505 | 0.55 | — | — | |
| SCHEMBL8773816 | 0.55 | — | — | |
| SCHEMBL21949099 | 0.55 | — | — | |
| SCHEMBL17655994 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3845529-A1 | METHYL/FLUORO-PYRIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS AND FLUORO-PYRIMIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | Aclaris Therapeutics, Inc. (US) | 2021-07-07 | — | — | EP | disclosed |