Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18630792 | 0.93 | CNR2 (0.37) | CNR2CNR1MAPT | |
| SCHEMBL18630790 | 0.93 | CNR2 (0.37) | CNR2CNR1MAPT | |
| SCHEMBL18631189 | 0.91 | CNR2 (0.38) | CNR2CNR1MAPTLMNATP53 | |
| SCHEMBL18631188 | 0.91 | CNR2 (0.38) | CNR2CNR1MAPTLMNATP53 | |
| SCHEMBL23618009 | 0.88 | KDM4E (0.33) | CNR2MAPT | |
| SCHEMBL18650882 | 0.81 | — | — | |
| SCHEMBL18650851 | 0.81 | CNR2 (0.40) | CNR2CNR1TRPV4 | |
| SCHEMBL18631271 | 0.81 | CNR2 (0.38) | CNR2CNR1MAPT | |
| SCHEMBL18641975 | 0.81 | CNR2 (0.37) | CNR2CNR1MAPTLMNATP53 | |
| SCHEMBL18631272 | 0.81 | CNR2 (0.38) | CNR2CNR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3350177-B1 | HETEROARYL COMPOUNDS AS IRAK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2021-07-07 | — | — | EP | disclosed |