Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL388837 | 0.85 | MAP2K1 (0.69) | MAP2K1MAP2K2 | |
| SCHEMBL388850 | 0.83 | MAP2K1 (0.51) | MAP2K1MAP2K2 | |
| SCHEMBL387684 | 0.83 | MAP2K1 (0.58) | MAP2K1MAP2K2 | |
| SCHEMBL394452 | 0.83 | MAP2K1 (0.55) | MAP2K1 | |
| SCHEMBL394451 | 0.83 | MAP2K1 (0.55) | MAP2K1 | |
| SCHEMBL392815 | 0.82 | MAP2K1 (0.71) | MAP2K1MAP2K2 | |
| SCHEMBL391436 | 0.81 | MAP2K1 (0.55) | MAP2K1MAP2K2 | |
| SCHEMBL393001 | 0.77 | MAP2K1 (0.47) | MAP2K1MAP2K2 | |
| SCHEMBL393000 | 0.77 | MAP2K1 (0.47) | MAP2K1MAP2K2 | |
| SCHEMBL387629 | 0.76 | MAP2K1 (0.58) | MAP2K1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361905-A1 | Heterocyclic Inhibitors of MEK and methods of use thereof | Array Biopharma Inc. (US) | 2011-08-31 | — | — | EP | disclosed |