SCHEMBL23618974

SCHEMBL23618974

Cc1cc(-c2cnn(C)c2)cn2ncc(C#N)c12

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RET P07949 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22031522 0.85 RET (0.55) RET
SCHEMBL22909529 0.84 RET (0.57) RET
SCHEMBL31590149 0.84 RET (0.57) RET
SCHEMBL29341087 0.83 RET (0.56) RET
SCHEMBL1907280 0.83 RET (0.56) RET
SCHEMBL29629368 0.81 RET (0.57) RET
SCHEMBL29629373 0.81 RET (0.52) RET
SCHEMBL29483272 0.81 RET (0.57) RET
SCHEMBL29629371 0.80 RET (0.56) RET
SCHEMBL29483260 0.80 RET (0.60) RET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021135938-A1 HETEROCYCLIC SULFOXIMINE COMPOUND AND INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 南京创济生物医药有限公司 2021-07-08 WO disclosed