Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 2/20 | 0.55 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.53 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.53 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.53 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.50 |
| ▸ | TYMP | P19971 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 2/20 | 0.47 |
| ▸ | STING1 | Q86WV6 | 6/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | DTYMK | P23919 | 2/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21759039 | 0.93 | POLB (0.56) | POLBF2P2RY2P2RY4P2RY6 | |
| SCHEMBL18521547 | 0.93 | POLB (0.61) | POLBF2P2RY2P2RY4P2RY6 | |
| SCHEMBL25812883 | 0.92 | F2 (0.55) | POLBF2P2RY2P2RY4P2RY6 | |
| SCHEMBL23619518 | 0.92 | F2 (0.55) | POLBF2P2RY2P2RY4P2RY6 | |
| SCHEMBL23619403 | 0.92 | F2 (0.55) | POLBF2P2RY2P2RY4P2RY6 | |
| SCHEMBL18521732 | 0.92 | POLB (0.58) | POLBF2P2RY2P2RY4P2RY6 | |
| SCHEMBL22072422 | 0.92 | POLB (0.58) | POLBF2P2RY2P2RY4P2RY6 | |
| SCHEMBL18521731 | 0.92 | POLB (0.58) | POLBF2P2RY2P2RY4P2RY6 | |
| SCHEMBL21758981 | 0.91 | POLB (0.58) | POLBF2P2RY2P2RY4P2RY6 | |
| SCHEMBL23619311 | 0.91 | F2 (0.49) | POLBF2P2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210206796-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2021-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210206796-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | STING1, CGAS, IFNAR1 | POLB 312/4885F2 2748/4885P2RY2 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.