Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 6/20 | 0.45 |
| ▸ | KCNJ3 | P48549 | 6/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | PRKX | P51817 | 1/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.38 |
| ▸ | RORA | P35398 | 1/20 | 0.38 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23620040 | 0.90 | KCNJ5 (0.43) | KCNJ5KCNJ3CLK2PRKXCAMK2D | |
| SCHEMBL23620039 | 0.88 | KCNJ5 (0.48) | KCNJ5KCNJ3CLK2PRKXCAMK2D | |
| SCHEMBL24713400 | 0.87 | KCNJ5 (0.47) | KCNJ5KCNJ3CLK2PRKXCAMK2D | |
| SCHEMBL30812926 | 0.83 | P2RX4 (0.53) | P2RX4 | |
| SCHEMBL23620069 | 0.83 | CSNK1D (0.46) | KCNJ5KCNJ3CLK2PRKXCAMK2D | |
| SCHEMBL23619701 | 0.83 | P2RX4 (0.53) | P2RX4 | |
| SCHEMBL23620204 | 0.83 | KCNJ5 (0.43) | KCNJ5KCNJ3CLK2PRKXCAMK2D | |
| SCHEMBL23619948 | 0.83 | KCNJ5 (0.49) | KCNJ5KCNJ3CLK2PRKXCAMK2D | |
| SCHEMBL24713423 | 0.82 | CLK2 (0.47) | KCNJ5KCNJ3CLK2PRKXCAMK2D | |
| SCHEMBL23448558 | 0.79 | KCNJ5 (0.47) | KCNJ5KCNJ3CLK2PRKXCAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4079724-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | Wuhan LL Science and Technology Development Co., Ltd. (CN) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021136238-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2021-07-08 | — | — | WO | disclosed |