Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KCNJ5 | P48544 | 4/20 | 0.43 |
| ▸ | KCNJ3 | P48549 | 4/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.42 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | PRKX | P51817 | 1/20 | 0.41 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23620069 | 0.91 | CSNK1D (0.46) | CSNK1DRECQLKCNJ5KCNJ3ROCK2 | |
| SCHEMBL23619776 | 0.86 | NR1I2 (0.46) | CSNK1DRECQLKCNJ5KCNJ3ROCK2 | |
| SCHEMBL23619775 | 0.84 | CSNK1D (0.48) | CSNK1DRECQLKCNJ5KCNJ3ROCK2 | |
| SCHEMBL30812826 | 0.82 | P2RX4 (0.56) | P2RX4 | |
| SCHEMBL23619777 | 0.82 | P2RX4 (0.56) | P2RX4 | |
| SCHEMBL24713538 | 0.82 | CSNK1D (0.48) | CSNK1DRECQLKCNJ5KCNJ3ROCK2 | |
| SCHEMBL24713237 | 0.81 | CSNK1D (0.44) | CSNK1DRECQLKCNJ5KCNJ3ROCK2 | |
| SCHEMBL23619730 | 0.81 | P2RX4 (0.48) | CSNK1DRECQLKCNJ5KCNJ3ROCK2 | |
| SCHEMBL23620030 | 0.81 | P2RX4 (0.42) | CSNK1DRECQLKCNJ5KCNJ3ROCK2 | |
| SCHEMBL23620039 | 0.77 | KCNJ5 (0.48) | CSNK1DKCNJ5KCNJ3KCNJ6CLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021136238-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2021-07-08 | — | — | WO | disclosed |