Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.53 |
| ▸ | CNR2 | P34972 | 6/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14521693 | 0.88 | CYP1A2 (0.55) | POLBTLR8CNR2CNR1CACNA1D | |
| SCHEMBL2338195 | 0.85 | CNR2 (0.59) | POLBTLR8CNR2CNR1CACNA1D | |
| SCHEMBL14447552 | 0.83 | TLR8 (0.48) | TLR8CNR2CNR1CACNA1DKDM4E | |
| SCHEMBL3498905 | 0.83 | CNR2 (0.52) | TLR8CNR2CNR1CACNA1DKDM4E | |
| SCHEMBL2360807 | 0.80 | CACNA1D (0.52) | CNR2CNR1CACNA1DKDM4EBACE1 | |
| SCHEMBL7338096 | 0.79 | SOS1 (0.49) | POLBTLR8CNR2CNR1CACNA1D | |
| SCHEMBL21307563 | 0.78 | POLB (0.62) | POLBTLR8KDM4EALDH1A1NUDT1 | |
| SCHEMBL356541 | 0.78 | JAK2 (0.52) | CNR2CNR1KDM4EALDH1A1TDP1 | |
| SCHEMBL30358044 | 0.77 | SOS1 (0.60) | POLBCNR2CNR1CACNA1DALDH1A1 | |
| SCHEMBL3083259 | 0.77 | SOS1 (0.60) | POLBCNR2CNR1CACNA1DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |