SCHEMBL23624432

SCHEMBL23624432

N#Cc1ccc(-c2ccc3c4c(ccc(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)c24)-c2ccccc2-3)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 15/20 0.47
ABCB1 P08183 9/20 0.47
ABCC1 P33527 4/20 0.42
ALDH1A3 P47895 1/20 0.39
GABRA1 P14867 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38
GABRA5 P31644 1/20 0.38
GABRA3 P34903 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
ADORA2A P29274 1/20 0.38
ADORA2B P29275 1/20 0.38
ADORA1 P30542 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23624429 0.97 ABCG2 (0.49) ABCG2ABCB1ABCC1ALDH1A3GABRA1
SCHEMBL23624423 0.95 ABCG2 (0.48) ABCG2ABCB1ABCC1ALDH1A3GABRA1
SCHEMBL23624373 0.95 ABCG2 (0.48) ABCG2ABCB1ABCC1ALDH1A3GABRA1
SCHEMBL23624445 0.95 ABCG2 (0.48) ABCG2ABCB1ABCC1ALDH1A3GABRA1
SCHEMBL23624422 0.95 ABCG2 (0.48) ABCG2ABCB1ABCC1ALDH1A3GABRA1
SCHEMBL23624433 0.93 ABCG2 (0.46) ABCG2ABCB1ABCC1TSHRMEN1
SCHEMBL23624431 0.92 ABCG2 (0.45) ABCG2ABCB1ABCC1TSHRMEN1
SCHEMBL23624374 0.92 ABCG2 (0.45) ABCG2ABCB1ABCC1ALDH1A3GABRA1
SCHEMBL23624430 0.90 ABCG2 (0.47) ABCG2ABCB1ABCC1GABRA1GABRG2
SCHEMBL23624428 0.89 ABCG2 (0.46) ABCG2ABCB1ABCC1ALDH1A3GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021135725-A1 ORGANIC COMPOUND, ELECTRONIC DEVICE AND ELECTRONIC APPARATUS USING SAME 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed