Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 6/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.41 |
| ▸ | GAPDH | P04406 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.40 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.40 |
| ▸ | DNPH1 | O43598 | 2/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18048089 | 0.92 | TYMP (0.42) | TYMPP2RY12GAPDHP2RY2P2RY1 | |
| SCHEMBL18797882 | 0.91 | TYMP (0.41) | TYMPP2RY12GAPDHP2RY2P2RY1 | |
| SCHEMBL23624675 | 0.90 | P2RY12 (0.47) | P2RY12GAPDHP2RY2P2RY1P2RY6 | |
| SCHEMBL18048087 | 0.90 | TYMP (0.39) | TYMPP2RY12GAPDHP2RY2P2RY1 | |
| SCHEMBL23624636 | 0.88 | TYMP (0.44) | TYMPP2RY12GAPDHP2RY2P2RY1 | |
| SCHEMBL18797869 | 0.88 | TYMP (0.39) | TYMPP2RY12GAPDHP2RY2P2RY1 | |
| SCHEMBL18797890 | 0.87 | TYMP (0.39) | TYMPP2RY12GAPDHP2RY2P2RY1 | |
| SCHEMBL18797892 | 0.86 | TYMP (0.39) | TYMPP2RY12GAPDHP2RY2P2RY1 | |
| SCHEMBL18797862 | 0.86 | TYMP (0.39) | TYMPP2RY12GAPDHP2RY2P2RY1 | |
| SCHEMBL18992206 | 0.86 | TYMP (0.40) | TYMPP2RY12GAPDHP2RY2P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11597932-B2 | Chirally-enriched double-stranded RNA agents | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-03-07 | — | — | US | disclosed |
| US-20210207144-A1 | CHIRALLY-ENRICHED DOUBLE-STRANDED RNA AGENTS | BANK OF AMERICA, N.A. | 2021-07-08 | — | — | US | disclosed |