SCHEMBL23625293

SCHEMBL23625293

OCC1CCC(c2ncc3c(Cl)nccn23)CO1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDE1C Q14123 11/20 0.35
PDE1A P54750 8/20 0.34
PDE1B Q01064 8/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25981707 0.89 PDE1C (0.34) PDE1CPDE1APDE1B
SCHEMBL25268632 0.84 PDE1C (0.32) PDE1CPDE1APDE1B
SCHEMBL397983 0.82 PDE1C (0.43) PDE1CPDE1APDE1B
SCHEMBL397982 0.82 PDE1C (0.43) PDE1CPDE1APDE1B
SCHEMBL16748877 0.81 PDE1C (0.44) PDE1CPDE1APDE1B
SCHEMBL23625454 0.79 TNK2 (0.33)
SCHEMBL23625289 0.78 CYP2C19 (0.37) PDE1CPDE1APDE1B
SCHEMBL401192 0.78 TNK2 (0.38) PDE1CPDE1APDE1B
SCHEMBL400651 0.77 PDE1C (0.43) PDE1CPDE1APDE1B
SCHEMBL25981616 0.77 SMYD2 (0.32) PDE1CPDE1APDE1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120118089-A BTK inhibitors 迪哲(江苏)医药股份有限公司 2025-06-10 CN disclosed
CN-114945574-B BTK inhibitors 迪哲(江苏)医药股份有限公司 2025-02-07 CN disclosed
EP-4087845-A1 BTK INHIBITORS DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) 2022-11-16 EP disclosed
CN-114945574-A BTK inhibitors 迪哲(江苏)医药股份有限公司 2022-08-26 CN disclosed
WO-2021136219-A1 BTK INHIBITORS DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) 2021-07-08 WO disclosed