Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.38 |
| ▸ | FOS | P01100 | 3/20 | 0.38 |
| ▸ | JUN | P05412 | 3/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.38 |
| ▸ | RELA | Q04206 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24852041 | 0.84 | SYK (0.49) | SYKKDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL31612079 | 0.84 | SYK (0.49) | SYKKDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL31465569 | 0.83 | SYK (0.47) | SYKKDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL24851197 | 0.82 | SYK (0.48) | SYKKDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL23618678 | 0.81 | SYK (0.45) | SYKKDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL30479295 | 0.79 | SYK (0.46) | SYKKDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL23620493 | 0.79 | SYK (0.46) | SYKKDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL23618785 | 0.79 | GSK3A (0.44) | SYKKDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL23620399 | 0.78 | SYK (0.54) | SYKKDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL14810384 | 0.78 | KDM4E (0.57) | SYKKDM4EALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021136461-A1 | PURINE DERIVATIVE AND MEDICAL USE THEREOF | 成都百裕制药股份有限公司 | 2021-07-08 | — | — | WO | disclosed |