SCHEMBL23625643

SCHEMBL23625643

Oc1ccc(-c2nnn(-c3ccccc3)n2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.61
ABCG2 Q9UNQ0 3/20 0.58
RAB9A P51151 7/20 0.58
MMP9 P14780 3/20 0.50
MMP2 P08253 2/20 0.50
MAPT P10636 5/20 0.49
PKM P14618 2/20 0.49
CHRNB2 P17787 1/20 0.47
CHRNA5 P30532 1/20 0.47
CHRNA4 P43681 1/20 0.47
ABCB1 P08183 1/20 0.47
HPGD P15428 1/20 0.45
MEN1 O00255 1/20 0.45
USP2 O75604 1/20 0.45
TP53 P04637 1/20 0.45
NFKB1 P19838 1/20 0.45
NFKB2 Q00653 1/20 0.45
KMT2A Q03164 1/20 0.45
RELA Q04206 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23625879 0.93 NPC1 (0.71) NPC1ABCG2RAB9AMMP9MMP2
SCHEMBL23625641 0.91 NPC1 (0.57) NPC1ABCG2RAB9AMMP9MMP2
SCHEMBL23625647 0.91 NPC1 (0.71) NPC1ABCG2RAB9AMMP9MMP2
SCHEMBL23625628 0.89 NPC1 (0.69) NPC1ABCG2RAB9AMMP9MMP2
SCHEMBL2210517 0.87 NPC1 (0.77) NPC1ABCG2RAB9AMMP9MMP2
Bromide SCHEMBL146883 0.85 NPC1 (0.74) NPC1ABCG2RAB9AMMP9MMP2
Hydrochloric Acid SCHEMBL8698166 0.85 NPC1 (0.74) NPC1ABCG2RAB9AMMP9MMP2
Hydrochloric Acid SCHEMBL1219233 0.85 NPC1 (0.74) NPC1ABCG2RAB9AMMP9MMP2
Bromide SCHEMBL28209866 0.85 NPC1 (0.74) NPC1ABCG2RAB9AMMP9MMP2
Bromide SCHEMBL28209867 0.85 NPC1 (0.74) NPC1ABCG2RAB9AMMP9MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124324-A1 PHOTOCLICK CHEMISTRY OF SILK FOR TEMPORARY UV TATTOOS TUFTS COLLEGE (US) 2026-05-07 US disclosed
EP-4605247-A1 ELASTOMERIC COMPOSITIONS FOR TYRES COMPRISING NNEEWW CROSS-LINKING FUNCTIONALISING AGENTS, ELASTOMERIC COMPOUNDS AND TYRES COMPRISING THEM Pirelli Tyre S.p.A. (IT) 2025-08-27 EP disclosed
WO-2024084386-A9 ELASTOMERIC COMPOSITIONS FOR TYRES COMPRISING NNEEWW CROSS-LINKING FUNCTIONALISING AGENTS, ELASTOMERIC COMPOUNDS AND TYRES COMPRISING THEM PIRELLI TYRE S.P.A. (IT) 2025-06-12 WO disclosed
WO-2024187194-A2 PHOTOCLICK CHEMISTRY OF SILK FOR TEMPORARY UV TATTOOS TRUSTEES OF TUFTS COLLEGE (US) 2024-09-12 WO disclosed
EP-4085093-B1 COMPOSITIONS FOR ELASTOMERIC COMPOUNDS INCLUDING POLYTETRAZOLE CROSS-LINKING AGENTS AND TYRES COMPRISING THE SAME PIRELLI (IT) 2023-11-08 EP disclosed
US-20230257552-A1 COMPOSITIONS FOR ELASTOMERIC COMPOUNDS COMPRISING TETRAZOLE COMPATIBILIZING AGENTS AND TYRES COMPRISING THE SAME PIRELLI TYRE S.P.A. (IT) 2023-08-17 US disclosed
US-20230257552-A1 COMPOSITIONS FOR ELASTOMERIC COMPOUNDS COMPRISING TETRAZOLE COMPATIBILIZING AGENTS AND TYRES COMPRISING THE SAME PIRELLI TYRE S.P.A. (IT) 2023-08-17 US disclosed
US-20230058851-A1 COMPOSITIONS FOR ELASTOMERIC COMPOUNDS INCLUDING POLYTETRAZOLE CROSS-LINKING AGENTS AND TYRES COMPRISING THE SAME PIRELLI TYRE S.P.A. (IT) 2023-02-23 US disclosed
WO-2021260635-A1 COMPOSITIONS FOR ELASTOMERIC COMPOUNDS COMPRISING TETRAZOLE COMPATIBILIZING AGENTS AND TYRES COMPRISING THE SAME PIRELLI TYRE S.P.A. (IT) 2021-12-30 WO disclosed
WO-2021137143-A1 COMPOSITIONS FOR ELASTOMERIC COMPOUNDS INCLUDING POLYTETRAZOLE CROSS-LINKING AGENTS AND TYRES COMPRISING THE SAME PIRELLI TYRE S.P.A. (IT) 2021-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124324-A1 PHOTOCLICK CHEMISTRY OF SILK FOR TEMPORARY UV TATTOOS PTMS, ITK, MATK NPC1 4479/4885ABCG2 3884/4885RAB9A 1581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.