SCHEMBL23625971

SCHEMBL23625971

Cc1ncc(N2c3ccccc3Oc3ccccc32)cn1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 12/20 0.41
MAPT P10636 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
P2RX1 P51575 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ALOX5 P09917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19317168 0.82 P2RX4 (0.41) P2RX4MAPTNPSR1SMN1; SMN2KDM4E
SCHEMBL25878177 0.81 P2RX4 (0.36) P2RX4MAPTNPSR1SMN1; SMN2P2RX1
SCHEMBL25054672 0.81 P2RX4 (0.41) P2RX4MAPTNPSR1SMN1; SMN2P2RX1
SCHEMBL23349970 0.79 P2RX4 (0.37) P2RX4MAPTNPSR1SMN1; SMN2KDM4E
SCHEMBL18251677 0.79 P2RX4 (0.37) P2RX4MAPTNPSR1SMN1; SMN2P2RX1
SCHEMBL23625962 0.78 P2RX4 (0.39) P2RX4MAPTNPSR1SMN1; SMN2P2RX1
SCHEMBL6123819 0.76 P2RX4 (0.47) P2RX4MAPTNPSR1SMN1; SMN2P2RX1
SCHEMBL10001963 0.76 P2RX4 (0.53) P2RX4MAPTSMN1; SMN2ALDH1A1
SCHEMBL19317121 0.74 GRM1 (0.40) P2RX4NPSR1ALDH1A1
SCHEMBL1573992 0.74 P2RX4 (0.47) P2RX4NPSR1P2RX1ALDH1A1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021135181-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed