SCHEMBL23628382

SCHEMBL23628382

CC1=CC=CC(C)(C)C1c1ccccc1C

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 3/20 0.33
GSK3B P49841 1/20 0.33
BACE1 P56817 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
DDB1 Q16531 1/20 0.32
CRBN Q96SW2 1/20 0.32
TSHR P16473 1/20 0.31
ACHE P22303 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2B P41595 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9861958 0.81 TSHR (0.33) HTR2CGSK3BBACE1DDB1CRBN
SCHEMBL7169952 0.76 GSK3B (0.30) GSK3BBACE1
Orthocresol SCHEMBL8025259 0.69 CYP1A2 (0.35) HSD17B10
SCHEMBL25737090 0.67
SCHEMBL8816870 0.65
O-Xylene SCHEMBL27949583 0.63 TSHR (0.34) TSHRACHE
SCHEMBL15440778 0.62
SCHEMBL9849476 0.61 TSHR (0.45) HTR2CTAAR1DDB1CRBNTSHR
SCHEMBL6672438 0.60 NPSR1 (0.42) HTR2CGSK3BBACE1NPSR1TAAR1
SCHEMBL9946124 0.59 NPSR1 (0.41) HTR2CGSK3BBACE1NPSR1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3023449-B1 POLYAMIDE-IMIDE RESIN, AND CURABLE RESIN COMPOSITION AND CURED PRODUCT OF SAME DAINIPPON INK & CHEMICALS (JP) 2021-07-14 EP disclosed