Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1L1 | Q9UHC9 | 9/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CDC25A | P30304 | 4/20 | 0.48 |
| ▸ | POLA1 | P09884 | 2/20 | 0.47 |
| ▸ | VDR | P11473 | 1/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15301588 | 1.00 | NPC1L1 (0.59) | NPC1L1USP2MEN1LMNATP53 | |
| SCHEMBL15301622 | 0.83 | NPC1L1 (0.57) | NPC1L1USP2MEN1LMNATP53 | |
| SCHEMBL23628418 | 0.83 | NPC1L1 (0.57) | NPC1L1USP2MEN1LMNATP53 | |
| SCHEMBL23628441 | 0.83 | NPC1L1 (0.57) | NPC1L1USP2MEN1LMNATP53 | |
| SCHEMBL15301612 | 0.83 | NPC1L1 (0.57) | NPC1L1USP2MEN1LMNATP53 | |
| SCHEMBL21814362 | 0.80 | NPC1L1 (0.62) | NPC1L1USP2MEN1LMNATP53 | |
| SCHEMBL21814361 | 0.80 | NPC1L1 (0.62) | NPC1L1USP2MEN1LMNATP53 | |
| SCHEMBL15301589 | 0.80 | NPC1L1 (0.51) | NPC1L1USP2MEN1LMNATP53 | |
| SCHEMBL16163915 | 0.80 | NPC1L1 (0.59) | NPC1L1USP2MEN1LMNATP53 | |
| SCHEMBL14976569 | 0.80 | NPC1L1 (0.59) | NPC1L1USP2MEN1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2625190-B1 | DERIVATIVES OF STEROID BENZYLAMINES, HAVING AN ANTIPARASITIC, ANTIBACTERIAL, ANTIMYCOTIC AND/OR ANTIVIRAL ACTION | UNIV JUSTUS LIEBIG GIESSEN (DE) | 2021-07-14 | — | — | EP | disclosed |