Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20717719 | 1.00 | TAAR1 (0.49) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL20718163 | 1.00 | TAAR1 (0.49) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| Hydrochloric Acid SCHEMBL29981448 | 0.99 | TAAR1 (0.48) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| Hydrochloric Acid SCHEMBL20700209 | 0.99 | TAAR1 (0.48) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| Hydrochloric Acid SCHEMBL20700026 | 0.99 | TAAR1 (0.48) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| Hydrochloric Acid SCHEMBL20700207 | 0.99 | TAAR1 (0.48) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL20700463 | 0.90 | TAAR1 (0.45) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL20700465 | 0.90 | TAAR1 (0.45) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL20700633 | 0.90 | TAAR1 (0.45) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| Hydrochloric Acid SCHEMBL20700196 | 0.89 | TAAR1 (0.44) | TAAR1ADRA2AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3661929-B1 | ISOCHROMAN COMPOUNDS AND USES THEREOF | SUNOVION PHARMACEUTICALS INC (US) | 2021-07-14 | — | — | EP | claimed |
| EP-3661929-B1 | ISOCHROMAN COMPOUNDS AND USES THEREOF | SUNOVION PHARMACEUTICALS INC (US) | 2021-07-14 | — | — | EP | disclosed |