Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.58 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23628902 | 0.96 | SCD (0.64) | SCDHTTPIK3CAPIK3CBPIK3CG | |
| SCHEMBL23628918 | 0.93 | HSD17B10 (0.56) | — | |
| SCHEMBL23628978 | 0.84 | SMN1; SMN2 (0.52) | — | |
| SCHEMBL23628888 | 0.80 | SCD (0.64) | SCDHTTPIK3CAPIK3CBPIK3CG | |
| SCHEMBL23628994 | 0.80 | — | — | |
| SCHEMBL23629049 | 0.79 | MEN1 (0.42) | SCDHTT | |
| SCHEMBL29947440 | 0.78 | HSD17B10 (0.61) | SCDHTT | |
| SCHEMBL14807016 | 0.78 | SCD (0.77) | SCDHTTPIK3CAPIK3CBPIK3CG | |
| SCHEMBL24729463 | 0.78 | HSD17B10 (0.61) | SCDHTT | |
| SCHEMBL24729491 | 0.77 | SCD (0.63) | SCDHTTPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3847172-A1 | NEW CLASS OF DNA GYRASE AND/OR TOPOISOMERASE IV INHIBITORS WITH ACTIVITY AGAINST GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA | Univerza v Ljubljani (SI) | 2021-07-14 | — | — | EP | disclosed |