SCHEMBL23629564

SCHEMBL23629564

Cc1cc(C(=O)Nc2nc3cc(C(N)=O)cc(OCCC(C)O)c3n2CCC[C@H]2COc3cc(C(N)=O)cc4nc(NC(=O)c5cc(C)nn5CCF)n2c34)n(CCF)n1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23629569 0.98 STING1 (0.57) STING1
SCHEMBL21789601 0.93 STING1 (0.55) STING1
SCHEMBL21789642 0.91 STING1 (0.59) STING1
SCHEMBL21776851 0.88 STING1 (0.61) STING1
SCHEMBL21776854 0.88 STING1 (0.61) STING1
SCHEMBL21776846 0.88 STING1 (0.66) STING1
SCHEMBL23637144 0.88 STING1 (0.55) STING1
SCHEMBL23855752 0.86 STING1 (0.68) STING1
SCHEMBL21790016 0.86 STING1 (0.64) STING1
SCHEMBL21790070 0.86 STING1 (0.72) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848366-A1 HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND Adlai Nortye Biopharma Co., Ltd. (CN) 2021-07-14 EP disclosed