SCHEMBL23629784

SCHEMBL23629784

Oc1ccccc1CNNCCNNCc1ccccc1O

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.65
CA2 P00918 6/20 0.65
TSHR P16473 2/20 0.64
CYP2D6 P10635 1/20 0.64
HIF1A Q16665 1/20 0.64
CA9 Q16790 5/20 0.61
KDM4E B2RXH2 1/20 0.61
HSD17B10 Q99714 1/20 0.61
MPO P05164 7/20 0.59
SLC6A4 P31645 1/20 0.55
HSPA5 P11021 1/20 0.52
PKM P14618 1/20 0.52
CYP2C19 P33261 1/20 0.48
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1147664 0.93 TSHR (0.73) CA12CA2TSHRCYP2D6HIF1A
SCHEMBL20960594 0.84 TSHR (0.67) CA12CA2TSHRCYP2D6HIF1A
SCHEMBL31532322 0.79 CA12 (1.00) CA12CA2TSHRCYP2D6HIF1A
SCHEMBL2794849 0.79 CA12 (1.00) CA12CA2TSHRCYP2D6HIF1A
SCHEMBL460754 0.78 TSHR (1.00) CA12CA2TSHRCYP2D6HIF1A
SCHEMBL30586211 0.77 CA12 (0.95) CA12CA2TSHRCYP2D6HIF1A
SCHEMBL14354016 0.77 CA12 (0.95) CA12CA2TSHRCYP2D6HIF1A
SCHEMBL30586212 0.77 CA12 (0.95) CA12CA2TSHRCYP2D6HIF1A
SCHEMBL30197711 0.77 CA12 (0.95) CA12CA2TSHRCYP2D6HIF1A
SCHEMBL30586214 0.77 CA12 (0.95) CA12CA2TSHRCYP2D6HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848349-B1 A PROCESS FOR THE PREPARATION OF SALTS OF N,N'-DISUBSTITUTED ETHYLENEDIAMINE-N,N'-DIACETIC ACID DERIVATIVES AND THEIR USE PRZED PRODUKCYJNO CONSULTINGOWE ADOB SP Z O O (PL) 2023-03-15 EP disclosed
EP-3848349-A1 A PROCESS FOR THE PREPARATION OF SALTS OF N,N'-DISUBSTITUTED ETHYLENEDIAMINE-N,N'-DIACETIC ACID DERIVATIVES AND THEIR USE Przedsiebiorstwo Produkcyjno-Consultingowe ADOB Sp. z o.o. Sp. jawna (PL) 2021-07-14 EP disclosed