Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 7/20 | 0.67 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATP4A | P20648 | 1/20 | 0.42 |
| ▸ | ATP4B | P51164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20382942 | 0.85 | MAPK14 (0.52) | GRM2MAPK14MAPTMAPK1TDP1 | |
| SCHEMBL20382949 | 0.82 | MAPK14 (0.50) | GRM2MAPK14MAPTMAPK1TDP1 | |
| SCHEMBL3072834 | 0.81 | MAPK14 (0.51) | GRM2MAPK14MAPTMAPK1TDP1 | |
| SCHEMBL20382945 | 0.80 | MAPK14 (0.47) | GRM2MAPK14MAPTMAPK1TDP1 | |
| SCHEMBL271730 | 0.80 | MAPK14 (0.68) | MAPK14MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL20382950 | 0.80 | MAPK14 (0.47) | GRM2MAPK14MAPTMAPK1TDP1 | |
| SCHEMBL20386674 | 0.80 | MAPK14 (0.47) | GRM2MAPK14MAPTMAPK1TDP1 | |
| SCHEMBL20382952 | 0.80 | MAPK14 (0.47) | GRM2MAPK14 | |
| SCHEMBL3072830 | 0.80 | MAPK14 (0.49) | GRM2MAPK14MAPTMAPK1TDP1 | |
| SCHEMBL3074370 | 0.80 | MAPK14 (0.47) | GRM2MAPK14MAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361913-A1 | Anti-infective agents | Abbott Laboratories (US) | 2011-08-31 | — | — | EP | disclosed |
| EP-1560827-B1 | ANTI-INFECTIVE AGENTS | ABBOTT LAB (US) | 2010-12-29 | — | — | EP | disclosed |