Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29948271 | 1.00 | KMT2A (0.55) | KMT2AATMCA2F2PRSS1 | |
| SCHEMBL30225533 | 0.93 | KMT2A (0.46) | KMT2AATMCA2F2PRSS1 | |
| SCHEMBL8366178 | 0.88 | KMT2A (0.55) | KMT2AATMCA2F2PRSS1 | |
| SCHEMBL4126919 | 0.81 | KMT2A (0.51) | KMT2AATMCA2F2PRSS1 | |
| SCHEMBL16669181 | 0.80 | KMT2A (0.50) | KMT2AATMCA2F2PRSS1 | |
| SCHEMBL30204309 | 0.80 | KMT2A (0.50) | KMT2AATMCA2F2PRSS1 | |
| SCHEMBL26204953 | 0.80 | KMT2A (0.50) | KMT2AATMCA2F2PRSS1 | |
| SCHEMBL30203859 | 0.80 | KMT2A (0.50) | KMT2AATMCA2F2PRSS1 | |
| SCHEMBL26204959 | 0.80 | KMT2A (0.50) | KMT2AATMCA2F2PRSS1 | |
| SCHEMBL16669303 | 0.80 | KMT2A (0.50) | KMT2AATMCA2F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021141506-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | Uniwersytet Jagielloński (PL) | 2021-07-15 | — | — | WO | claimed |
| WO-2021141506-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | Uniwersytet Jagielloński (PL) | 2021-07-15 | — | — | WO | disclosed |