Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 19/20 | 0.64 |
| ▸ | MTOR | P42345 | 14/20 | 0.64 |
| ▸ | PIK3CA | P42336 | 14/20 | 0.64 |
| ▸ | ATR | Q13535 | 3/20 | 0.60 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.60 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.60 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.60 |
| ▸ | PRKDC | P78527 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23634728 | 0.90 | ATM (0.76) | ATMMTORPIK3CAATRPIK3CD | |
| SCHEMBL23634730 | 0.90 | ATM (0.63) | ATMMTORPIK3CAATRPIK3CD | |
| SCHEMBL23634716 | 0.87 | ATM (0.62) | ATMMTORPIK3CAATRKCNH2 | |
| SCHEMBL23634678 | 0.87 | ATM (0.74) | ATMMTORPIK3CAATRPIK3CD | |
| SCHEMBL23634692 | 0.87 | ATM (0.49) | ATMMTORPIK3CAATRPIK3CD | |
| SCHEMBL23634679 | 0.86 | ATM (0.59) | ATMMTORPIK3CAATRKCNH2 | |
| SCHEMBL23634680 | 0.86 | ATM (0.59) | ATMMTORPIK3CAATRKCNH2 | |
| SCHEMBL23634686 | 0.86 | ATM (0.59) | ATMMTORPIK3CAATRKCNH2 | |
| SCHEMBL23634705 | 0.85 | ATM (0.63) | ATMMTORPIK3CAATRPIK3CD | |
| SCHEMBL23634696 | 0.83 | ATM (0.45) | ATMMTORPIK3CAATRPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021139814-A1 | QUINOLINE IMIDAZOLE COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2021-07-15 | — | — | WO | disclosed |