Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29915269 | 0.84 | POLB (0.40) | POLBL3MBTL1PDPK1DAPK3PRKD3 | |
| SCHEMBL27092834 | 0.84 | POLB (0.40) | POLBL3MBTL1PDPK1DAPK3PRKD3 | |
| SCHEMBL21358444 | 0.80 | PDPK1 (0.47) | PDPK1MAPTNPSR1DAPK3PRKD3 | |
| SCHEMBL18114239 | 0.77 | CSF1R (0.46) | CSF1REGFRERBB2 | |
| SCHEMBL248603 | 0.75 | PDPK1 (0.53) | PDPK1DAPK3PRKD3FLT1RPS6KA3 | |
| SCHEMBL18114308 | 0.73 | CSF1R (0.39) | PDPK1CSF1REGFRERBB2 | |
| Ammonia Solution, Strong SCHEMBL19947552 | 0.72 | PDPK1 (0.41) | PDPK1FLT1KITCSF1REGFR | |
| SCHEMBL19959513 | 0.72 | AAK1 (0.43) | CSF1REGFRERBB2 | |
| SCHEMBL27092833 | 0.72 | EGFR (0.40) | FLT1CSF1REGFRERBB2 | |
| SCHEMBL24659389 | 0.71 | SLC2A1 (0.50) | POLBL3MBTL1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021139814-A1 | QUINOLINE IMIDAZOLE COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2021-07-15 | — | — | WO | disclosed |